The Inflammatory Origins of Periodontal Disease and Diabetes: A Framework for Understanding Clinical Outcomes

Inflammatory diseases share many common traits, including the ability to produce pro-inflammatory messengers called cytokines that travel throughout the body. Cytokines play an important role in physiologic regulation of many biological activities, but in inflammatory diseases, they are produced at levels that can have pathological consequences. In diabetes, cytokines can cause β-cell death and insulin resistance. In periodontal disease, the same cytokines are responsible for collagen destruction and alveolar bone loss. Because inflammatory diseases share a common biological denominator, they can often influence the progression of other inflammatory diseases. Educational Objectives At the conclusion of this course participants will understand: 1. The role of inflammatory cytokines in periodontal bone destruction and insulin resistance in diabetes. 2. The effect of periodontal disease on blood sugar levels. 3. How to advise patients and predict treatment outcomes for perio patients with diabetes. Author Profile Jeffrey A. Sibner, D.M.D. is an Adjunct Assistant Professor at the University of Pennsylvania School of Dental Medicine where he teaches a course on periodontal disease and diabetes. He is affiliated with St. Mary Medical Center and teaches a lay course called Diabetes and You through their diabetes education program. Dr. Sibner maintains a private practice in general dentistry in Bucks County, Pennsylvania. Author Disclosure Jeffrey A. Sibner has no potential conflicts of interest to disclose. Publication date: Oct. 2012 Expiration date: Sept. 2015 This educational activity was developed by PennWell’s Dental Group with no commercial support. This course was written for dentists, dental hygienists and assistants, from novice to skilled. Educational Methods: This course is a self-instructional journal and web activity. Provider Disclosure: PennWell does not have a leadership position or a commercial interest in any products or services discussed or shared in this educational activity nor with the commercial supporter. No manufacturer or third party has had any input into the development of course content. Requirements for Successful Completion: To obtain 2 CE credits for this educational activity you must pay the required fee, review the material, complete the course evaluation and obtain a score of at least 70%. CE Planner Disclosure: Heather Hodges, CE Coordinator does not have a leadership or commercial interest with with products or services discussed in this educational activity. Heather can be reached at [email protected] Educational Disclaimer: Completing a single continuing education course does not provide enough information to result in the participant being an expert in the field related to the course topic. It is a combination of many educational courses and clinical experience that allows the participant to develop skills and expertise. Registration: The cost of this CE course is $49.00 for 2 CE credits. Cancellation/Refund Policy: Any participant who is not 100% satisfied with this course can request a full refund by contacting PennWell in writing. Supplement to PennWell Publications PennWell designates this activity for 2 Continuing Educational Credits Dental Board of California: Provider 4527, course registration number 02-4527-12071 “This course meets the Dental Board of California’s requirements for 2 units of continuing education.” The PennWell Corporation is designated as an Approved PACE Program Provider by the Academy of General Dentistry. The formal continuing dental education programs of this program provider are accepted by the AGD for Fellowship, Mastership and membership maintenance credit. Approval does not imply acceptance by a state or provincial board of dentistry or AGD endorsement. The current term of approval extends from (11/1/2011) to (10/31/2015) Provider ID# 320452. Go Green, Go Online to take your course